The Portuguese centre-half is expected to leave the Spanish capital at the end of the season, with the Red Devils keen on securing a deal to bring him to Old Trafford
Jose Mourinho is keen on making Real Madrid defender Pepe a Manchester United in the summer, according to reports from The Sun.
The 33-year-old has fallen out of favour under Zinedine Zidane, having made just eight La Liga appearances this season, and is reportedly seen as the perfect addition for United by his countryman.
Pepe led Portugal to the Euro 2016 trophy in the summer and also won the Champions League with Real, though Raphael Varane and Sergio Ramos are the preferred pairing in the Los Blancos defence.
There is said to be interest in Pepe from China, though Mourinho reportedly hopes his personal relationship with the player will secure a transfer at the end of the season.